Recent Abstracts

  1. McIlwee HA, Badrossamay MR, Goss, JA, Parker KK. Parametric Study of Nanofiber Formation by Rotary Jet-Spinning. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  2. McIlwee HA, Badrossamay MR, Deravi LF, Goss, JA, Parker KK. Novel Method of Fibronectin Fibrillogenesis by Rotary Jet-Spinning. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  3. Farouz Y, Agarwal A, McCain ML, Parker KK. Alginate-based muscular thin films for in vitro cardiac contractility assays. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  4. Badrossamay MR, Goss JA, Parker KK. Pull-Spinning: A Rapid Prototyping of Nano-Scale Fibrous Assemblies. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  5. Badrossamay MR, McCain M, Parker KK. Bio-Hybrid Materials for Cardiac Tissue Engineering: Bio-Functionality and in-vitro Bio-degradation. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  6. Deravi LF, Bell G, Magyar A, McIlwee HA, Mathger L, Kuzirian A, Hu E, Hanlon R, Parker, KK. Assembly of Bio-Photonic Materials using Proteins Isolated from cuttlefish Sepia officinalis. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  7. McIlwee HA, Badrossamay MR, Deravi LF, Goss, JA, Parker KK. Novel Method of Fibronectin Fibrillogenesis by Rotary Jet-Spinning. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  8. Farouz Y, Agarwal A, McCain ML, Parker KK. Alginate-based muscular thin films for in vitro cardiac contractility assays. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  9. Sheehy SP, Qin P, Gordon E, Grosberg A, Yoon L, Falls JG, Goss JA, Pipes T, Xu X, Willette R, Hu E, Parker KK. Anisotropy Promotes a Mature Gene Expression Profile in Cultured Neonatal Rat Ventricular Myocytes. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  10. Grosberg A, Alford PW, McCain ML, Nesmith AP, Parker, KK. Heart on a Chip: Measuring Structure-Function Relationship of Cardiac Tissue. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  11. Deravi LF, Alford PW, Dabiri B, Grosberg A, Parker KK. Molecular Changes in Protein nanoFabrics. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  12. Deravi LF, Hemphill MA, Grosberg A, Dabiri B, Parker KK. In vitro Models of Neurodegenerative Diseases with Engineered Amyloid Beta Plaques. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  13. Badrossamay MR, Exilus R, Goss JA, McCain M, Parker KK. ECM-Hybrid Scaffold for Cardiac Tissue Engineering. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  14. Badrossamay MR, Deravi L, McIlwee HA, Feinberg, AW, Goss JA, Parker KK. De novo Assembly of Extracellular Matrix Proteins, New Frontiers in Fiber Material Science, Charleston, SC, October 2011.
  15. Deravi LF, Alford PW, Dabiri B, Grosberg A, Parker KK. Molecular Changes in Protein nanoFabrics, American Chemical Society Meeting (ACS), Denver, CO, August 2011.
  16. McIlwee HA, Badrossamay MR, Goss, JA, Parker KK. Parametric Study of Nanofiber Formation by Rotary Jet-Spinning. International Materials Research Congress (IMRC) Annual Meeting, Cancun, Mexico. August 2011.
  17. Dabiri BE, Kerscher L, Franck C, Hemphill MA, Goss JA, Alford PW, Parker KK. In Vitro Focal Adhesion Complex Manipulation in Single Neurons: A Model for Traumatic Brain Injury. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  18. Hemphill MA, Dabiri BE, Goss JA, Alford PW, Parker KK. Integrin Mediated Injury in Neurons: A Role for Mechanotransduction in Mild Traumatic Brain Injury. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  19. Grosberg A, Brigham M, Parker KK. A tissue scale, in vitro, combination contractility and electrophysiological assay. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  20. Grosberg A, McCain ML, Parker KK. Self-Organization of a Two Cell Muscle Tissue: Theory and Experiment. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  21. McCain ML, Desplantez T, Geisse NA, Hinnen H, Kleber AG, Parker KK. Electrical Coupling of Ventricular Myocytes is Dependent on Cx43 Density and Myofibril Organization. Biomedical Engineering Society (BMES) Meeting, Austin, TX. October 2010.
  22. McCain ML, Brigham M, Feinberg AW, Alford PW, Sheehy SP, Grosberg A, Goss JA, Parker KK. Engineering Cardiac Form and Function through Cyclic Stretch and Extracellular Matrix Patterning. Biomedical Engineering Society (BMES) Meeting, Austin, TX. October 2010.
  23. Badrossamay MR, McIlwee HA, Goss, JA, Parker KK. Rotary Jet-Spinning: A Novel Technique of Nanofibrous Scaffold Fabrication. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  24. Balachandran K, Wylie-Sears J, Bischoff J, Aikawa E, Levine RA, Parker KK. Cyclic Stretch Induces Endothelial to Mesenchymal Transdifferentiation in Mitral Valve Endothelial Cells. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  25. Alford PW, Goss JA, Brigham MD, Feinberg AW, Parker KK. In Vitro Vasospasms: Acute Traumatic Injury and Vascular Hypercontractility. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  26. Alford PW, Goss JA, Brigham MD, Feinberg AW, Parker KK. In Vitro Vasospasms: Acute Traumatic Injury and Vascular Hypercontractility. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  27. Grosberg A, Brigham M, Goss JA, Alford PA, Parker KK. A tissue scale, in vitro, multiplex contractility assay. Safety Pharmacology Society Annual Meeting, Boston, MA. September 2010.
  28. Grosberg A, Brigham M, Parker KK. Translation to higher throughput: An In vitro, combination contractility and electrophysiological assay. ISACB Biannual Meeting, Cambridge, MA. September 2010.
  29. Balachandran K, Wylie-Sears J, Bischoff J, Aikawa E, Levine R, Parker KK. Cyclic Stretch Induces Alignment and Differentiation of Mitral Valve Endothelial Cells. ISACB Biannual Meeting, Cambridge, MA. September 2010.
  30. Alford PW, Goss JA, Brigham M, Feinberg AW, Parker KK. Hypercontractility Due To Acute Vascular Injury In Vitro: Mechanisms for Cerebral Vasospasms in Traumatic Brain Injury. National Neurotrauma Symposium, Las Vegas, NV. June 2010.
  31. Hemphill MA, Dabiri BE, Goss JA, Alford PW, Parker KK. Acute Mechanical Injury in Neurons: A Role For Integrin Signaling In Traumatic Brain Injury. National Neurotrauma Symposium, Las Vegas, NV. June 2010.
  32. Dabiri BE, Hemphill MA, Kerscher L, Franck C, Goss JA, Alford PW, Parker KK. Focal Adhesion Complex Activation in Single Neurons: A Mechanism for Traumatic Brain Injury. National Neurotrauma Symposium, Las Vegas, NV. June 2010.
  33. Hemphill MA, Dabiri BE, Kerscher L, Franck C, Goss JA, Parker KK. Maladaptive Neural Remodeling in Response to Integrin-Mediated Injury In Vitro. Keystone Synapse: Formation, Function, and Misfunction Snowbird, UT. April 2010.
  34. Feinberg AW, Parker KK. De Novo Regeneration of the Hierarchical Extracellular Matrix with Protein nanoFabrics. Materials Research Society (MRS) Fall Meeting, Boston, MA. November 2009.
  35. Grosberg A, Feinberg AW, Goss JA, Alford PW, Parker KK. A Device for in vitro, High Throughput Cell Tissue Contractility Assay. Materials Research Society (MRS) Fall Meeting, Boston, MA. November 2009.
  36. Badrossamay MR, Goss JA, Parker KK. Fabrication of Well-aligned 3D Nanofibrous Scaffold through Jet-Spinning System. Materials Research Society (MRS) Fall Meeting, Boston, MA. November 2009.
  37. McCain ML, Desplantez T, Beauchamp P, Geisse NA, Rigoli G, Parker KK, Kleber AG. Electrical properties and connexin distribution in micropatterned atrial myocytes with altered connexin 43 genotypes. Heart Rhythm Society’s Scientific Sessions, Boston, MA. May 2009.
  38. McCain ML, Desplantez T, Geisse NA, Oberer H, Parker KK, Kleber AG. Relating electrical conductance, connexin 43 immunostaining, and cell shape in micropatterned cardiac cell pairs. Biophysical Society Annual Meeting, Boston, MA. March 2009.
  39. Adams WJ, O’Grady ML, Kaustabh G, Gibbs AD, Ingber DE, Parker KK. Viscoelastic indentation of extremely soft biological samples. Biophysical Society Annual Meeting, Boston, MA. March 2009.
  40. Feinberg AW, Alford PW, Ripplinger CM, Adams WJ, Sheehy SP, Parker KK. Engineering cardiac contractility from the sarcomere to tissue-scale. Biophysical Society 53rd Annual Meeting, Boston, MA. March 2009.
  41. Feinberg AW, Ripplinger CM, Sheehy SP, Parker KK. Microscale heterogeneities enhance sarcomere alignment and contractile force in engineered myocardium. Materials Research Society (MRS) Fall Meeting, Boston, MA. December 2008.
  42. O’Grady ML, Parker KK. Hierarchical biomimetic design of artificial muscle hydrogels. Materials Research Society (MRS) Fall Meeting, Boston, MA. December 2008.
  43. Feinberg AW, Sheehy SP, Parker KK. Sarcomere alignment dictates contractile force in engineered myocardium. Biomedical Engineering Society (BMES) Annual Meeting, St Louis, MO. October 2008.
  44. Feinberg AW, Sheehy SP, Parker KK. Engineered boundary conditions direct cardiac myogenesis and contractility. Union of the Swiss Societies for Experimental Biology – Biology Meets Engineering, Lausanne, Switzerland. February 2008.
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What's New

DBG Lab is Operational! March 15th, 2021

After 17 years of outstanding science in Cambridge, the DBG has moved to the Engineering School’s new campus in Allston. As of March 2, the lab is fully operational and has resumed experiments. Thank you to all alumni and current personnel for constantly raising the bar. Stand by for the next chapter of DBG science!

Congratulations to Dr. Megan McCain! March 10th, 2021

Our congratulations go out to DBG alumna, Dr. Megan McCain, who has recently received tenure at University of Southern California!

Farewell to Dr. Suhwan Kim! January 13th, 2021

Congratulations to Dr. Suhwan Kim, who has accepted a position as an Assistant Professor in the Department of Chemical Engineering at Dong-A University in Basun, South Korea! Dr. Kim was an integral part of our brain team for over a year as a postdoctoral fellow. We wish him the best on this next step in his career!

Inaugural Issue — Biophysics Reviews! January 4th, 2021

Dr. Kevin Kit Parker launched Biophysics Reviews, a new peer-reviewed journal for the biophysics research community on December 14. Produced by scientific publisher AIP Publishing, the aims to expand “on the tradition of excellence set by Applied Physics Reviews (APR) by publishing high impact, cutting edge research and reviews that are valuable for both emerging and experienced researchers”.

References:
1. KK Parker, L Longobardi, A Sulicz. “Welcome to Biophysics Reviews, a big tent for the biophysics community”. Biophysics Reviews. 14 Dec 2020; 1(1); 010401. https://doi.org/10.1063/5.0036408.

A Belated Farewell and Congratulations to Dr. Ardoña! October 14th, 2020

Congratulations to Dr. Herdeline Ardoña, who has accepted a position as an Assistant Professor in the University of California Irvine Department of Chemical and Biomolecular Engineering. She joined the Disease Biophysics Group as a postdoctoral fellow in 2017 and was an essential part of our research and mentoring team. Best of luck to you as you settle in and get your research group up and running!