Recent Abstracts

  1. McIlwee HA, Badrossamay MR, Goss, JA, Parker KK. Parametric Study of Nanofiber Formation by Rotary Jet-Spinning. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  2. McIlwee HA, Badrossamay MR, Deravi LF, Goss, JA, Parker KK. Novel Method of Fibronectin Fibrillogenesis by Rotary Jet-Spinning. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  3. Farouz Y, Agarwal A, McCain ML, Parker KK. Alginate-based muscular thin films for in vitro cardiac contractility assays. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  4. Badrossamay MR, Goss JA, Parker KK. Pull-Spinning: A Rapid Prototyping of Nano-Scale Fibrous Assemblies. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  5. Badrossamay MR, McCain M, Parker KK. Bio-Hybrid Materials for Cardiac Tissue Engineering: Bio-Functionality and in-vitro Bio-degradation. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  6. Deravi LF, Bell G, Magyar A, McIlwee HA, Mathger L, Kuzirian A, Hu E, Hanlon R, Parker, KK. Assembly of Bio-Photonic Materials using Proteins Isolated from cuttlefish Sepia officinalis. Materials Research Society (MRS) Fall Meeting, Boston, MA, November 2011.
  7. McIlwee HA, Badrossamay MR, Deravi LF, Goss, JA, Parker KK. Novel Method of Fibronectin Fibrillogenesis by Rotary Jet-Spinning. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  8. Farouz Y, Agarwal A, McCain ML, Parker KK. Alginate-based muscular thin films for in vitro cardiac contractility assays. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  9. Sheehy SP, Qin P, Gordon E, Grosberg A, Yoon L, Falls JG, Goss JA, Pipes T, Xu X, Willette R, Hu E, Parker KK. Anisotropy Promotes a Mature Gene Expression Profile in Cultured Neonatal Rat Ventricular Myocytes. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  10. Grosberg A, Alford PW, McCain ML, Nesmith AP, Parker, KK. Heart on a Chip: Measuring Structure-Function Relationship of Cardiac Tissue. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  11. Deravi LF, Alford PW, Dabiri B, Grosberg A, Parker KK. Molecular Changes in Protein nanoFabrics. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  12. Deravi LF, Hemphill MA, Grosberg A, Dabiri B, Parker KK. In vitro Models of Neurodegenerative Diseases with Engineered Amyloid Beta Plaques. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  13. Badrossamay MR, Exilus R, Goss JA, McCain M, Parker KK. ECM-Hybrid Scaffold for Cardiac Tissue Engineering. Biomedical Engineering Society (BMES) Annual Meeting, Hartford, CT, October 2011.
  14. Badrossamay MR, Deravi L, McIlwee HA, Feinberg, AW, Goss JA, Parker KK. De novo Assembly of Extracellular Matrix Proteins, New Frontiers in Fiber Material Science, Charleston, SC, October 2011.
  15. Deravi LF, Alford PW, Dabiri B, Grosberg A, Parker KK. Molecular Changes in Protein nanoFabrics, American Chemical Society Meeting (ACS), Denver, CO, August 2011.
  16. McIlwee HA, Badrossamay MR, Goss, JA, Parker KK. Parametric Study of Nanofiber Formation by Rotary Jet-Spinning. International Materials Research Congress (IMRC) Annual Meeting, Cancun, Mexico. August 2011.
  17. Dabiri BE, Kerscher L, Franck C, Hemphill MA, Goss JA, Alford PW, Parker KK. In Vitro Focal Adhesion Complex Manipulation in Single Neurons: A Model for Traumatic Brain Injury. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  18. Hemphill MA, Dabiri BE, Goss JA, Alford PW, Parker KK. Integrin Mediated Injury in Neurons: A Role for Mechanotransduction in Mild Traumatic Brain Injury. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  19. Grosberg A, Brigham M, Parker KK. A tissue scale, in vitro, combination contractility and electrophysiological assay. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  20. Grosberg A, McCain ML, Parker KK. Self-Organization of a Two Cell Muscle Tissue: Theory and Experiment. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  21. McCain ML, Desplantez T, Geisse NA, Hinnen H, Kleber AG, Parker KK. Electrical Coupling of Ventricular Myocytes is Dependent on Cx43 Density and Myofibril Organization. Biomedical Engineering Society (BMES) Meeting, Austin, TX. October 2010.
  22. McCain ML, Brigham M, Feinberg AW, Alford PW, Sheehy SP, Grosberg A, Goss JA, Parker KK. Engineering Cardiac Form and Function through Cyclic Stretch and Extracellular Matrix Patterning. Biomedical Engineering Society (BMES) Meeting, Austin, TX. October 2010.
  23. Badrossamay MR, McIlwee HA, Goss, JA, Parker KK. Rotary Jet-Spinning: A Novel Technique of Nanofibrous Scaffold Fabrication. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  24. Balachandran K, Wylie-Sears J, Bischoff J, Aikawa E, Levine RA, Parker KK. Cyclic Stretch Induces Endothelial to Mesenchymal Transdifferentiation in Mitral Valve Endothelial Cells. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  25. Alford PW, Goss JA, Brigham MD, Feinberg AW, Parker KK. In Vitro Vasospasms: Acute Traumatic Injury and Vascular Hypercontractility. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  26. Alford PW, Goss JA, Brigham MD, Feinberg AW, Parker KK. In Vitro Vasospasms: Acute Traumatic Injury and Vascular Hypercontractility. Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX. October 2010.
  27. Grosberg A, Brigham M, Goss JA, Alford PA, Parker KK. A tissue scale, in vitro, multiplex contractility assay. Safety Pharmacology Society Annual Meeting, Boston, MA. September 2010.
  28. Grosberg A, Brigham M, Parker KK. Translation to higher throughput: An In vitro, combination contractility and electrophysiological assay. ISACB Biannual Meeting, Cambridge, MA. September 2010.
  29. Balachandran K, Wylie-Sears J, Bischoff J, Aikawa E, Levine R, Parker KK. Cyclic Stretch Induces Alignment and Differentiation of Mitral Valve Endothelial Cells. ISACB Biannual Meeting, Cambridge, MA. September 2010.
  30. Alford PW, Goss JA, Brigham M, Feinberg AW, Parker KK. Hypercontractility Due To Acute Vascular Injury In Vitro: Mechanisms for Cerebral Vasospasms in Traumatic Brain Injury. National Neurotrauma Symposium, Las Vegas, NV. June 2010.
  31. Hemphill MA, Dabiri BE, Goss JA, Alford PW, Parker KK. Acute Mechanical Injury in Neurons: A Role For Integrin Signaling In Traumatic Brain Injury. National Neurotrauma Symposium, Las Vegas, NV. June 2010.
  32. Dabiri BE, Hemphill MA, Kerscher L, Franck C, Goss JA, Alford PW, Parker KK. Focal Adhesion Complex Activation in Single Neurons: A Mechanism for Traumatic Brain Injury. National Neurotrauma Symposium, Las Vegas, NV. June 2010.
  33. Hemphill MA, Dabiri BE, Kerscher L, Franck C, Goss JA, Parker KK. Maladaptive Neural Remodeling in Response to Integrin-Mediated Injury In Vitro. Keystone Synapse: Formation, Function, and Misfunction Snowbird, UT. April 2010.
  34. Feinberg AW, Parker KK. De Novo Regeneration of the Hierarchical Extracellular Matrix with Protein nanoFabrics. Materials Research Society (MRS) Fall Meeting, Boston, MA. November 2009.
  35. Grosberg A, Feinberg AW, Goss JA, Alford PW, Parker KK. A Device for in vitro, High Throughput Cell Tissue Contractility Assay. Materials Research Society (MRS) Fall Meeting, Boston, MA. November 2009.
  36. Badrossamay MR, Goss JA, Parker KK. Fabrication of Well-aligned 3D Nanofibrous Scaffold through Jet-Spinning System. Materials Research Society (MRS) Fall Meeting, Boston, MA. November 2009.
  37. McCain ML, Desplantez T, Beauchamp P, Geisse NA, Rigoli G, Parker KK, Kleber AG. Electrical properties and connexin distribution in micropatterned atrial myocytes with altered connexin 43 genotypes. Heart Rhythm Society’s Scientific Sessions, Boston, MA. May 2009.
  38. McCain ML, Desplantez T, Geisse NA, Oberer H, Parker KK, Kleber AG. Relating electrical conductance, connexin 43 immunostaining, and cell shape in micropatterned cardiac cell pairs. Biophysical Society Annual Meeting, Boston, MA. March 2009.
  39. Adams WJ, O’Grady ML, Kaustabh G, Gibbs AD, Ingber DE, Parker KK. Viscoelastic indentation of extremely soft biological samples. Biophysical Society Annual Meeting, Boston, MA. March 2009.
  40. Feinberg AW, Alford PW, Ripplinger CM, Adams WJ, Sheehy SP, Parker KK. Engineering cardiac contractility from the sarcomere to tissue-scale. Biophysical Society 53rd Annual Meeting, Boston, MA. March 2009.
  41. Feinberg AW, Ripplinger CM, Sheehy SP, Parker KK. Microscale heterogeneities enhance sarcomere alignment and contractile force in engineered myocardium. Materials Research Society (MRS) Fall Meeting, Boston, MA. December 2008.
  42. O’Grady ML, Parker KK. Hierarchical biomimetic design of artificial muscle hydrogels. Materials Research Society (MRS) Fall Meeting, Boston, MA. December 2008.
  43. Feinberg AW, Sheehy SP, Parker KK. Sarcomere alignment dictates contractile force in engineered myocardium. Biomedical Engineering Society (BMES) Annual Meeting, St Louis, MO. October 2008.
  44. Feinberg AW, Sheehy SP, Parker KK. Engineered boundary conditions direct cardiac myogenesis and contractility. Union of the Swiss Societies for Experimental Biology – Biology Meets Engineering, Lausanne, Switzerland. February 2008.
Grp_photo_Jan 2014_305W_230H

What's New

The DBG welcomes the Orientation and Reach-Back Training class of the U.S. Army May 22nd, 2017

The DBG had the pleasure of hosting the Orientation and Reach-Back Training (ORBT) training class of the U.S. Army Research, Development and Engineering Command (RDECOM) Field Assistance in Science and Technology (FAST) program on May 17, 2017. ORBT is a multi-week mission overview program for senior-level Army officers, non-commissioned officers and Department of the Army civilians on the mechanisms for identifying and resolving technology capability gaps for units in their area of operation. The class visit to Professor (Lieutenant Colonel, Reserves) Parker’s Lab is their only visit to a Lab outside the Department of Defense.

The class met with DBG veterans and attended presentations on Stronger, Tougher, and Lighter Soldier Protection Systems; Nanofiber Scaffolds for Wound Healing/Dressings; Traumatic Brain Injury – Understanding Disease Mechanisms; Fibrous Scaffolds for Tissue Engineered Foods; Cells as Engineering Materials – the Cyborg Ray Project; Cuttlefish Inspired Camouflage; and our unique program for embedding Artists-In- Residence in the Lab.

Guests included members from the U.S. Army Research, Development, and Engineering Command (RDECOM); U.S. Army Engineer Research and Development Center (ERDC); U.S. Army Corps of Engineers; Army Research Laboratory; and RDECOM Research, Development and Engineering Centers.

Pictured below are (clockwise from bottom left): DBG Artist-in- Residence Karaghen Hudson (Harvard Class of 2018); Ms. Valerie Carney (ERDC); Dr. Aimee Poda (ERDC); Dr. (Colonel, Reserves) Steve Hart (RDECOM); Veteran and Program Coordinator John Laursen (Army Retired); Dr. Jerry Ballard (ERDC); Mr. Nathan Frantz (US Army Corps of Engineers); Visiting Scholar and Brigadier General Michael D. Phillips (USA Retired); Dr. Samantha Chambers RDECOM Science Advisor to the XVIII Airborne Corps; and Lieutenant Colonel Jovanna Nelson.

Congratulations to Stephanie Dauth, Ben Maoz, & Sean Sheehy on the cover of the Journal of Neurophysiology May 11th, 2017

Congratulations to our Brain Team for getting the cover of this month’s Journal of Neurophysiology “Neurons derived from different brain regions are inherently different in vitro: A novel multiregional brain-on-a-chip

Close-up image of axons that
have been grown over a 1-mm gap on a microcontact printed PLL/laminin lines connecting the different brain regions

Robotic Stingray wins Gold Medal at Edison Awards! April 25th, 2017

Congratulations to Professor Kit Parker and Sung-Jin Park, Ph.D. who received a gold medal in the engineering category at the Edison Awards for their work on the cyborg stingray.  The Edison Awards honor excellence in new product and service development, marketing, human-centered design and innovation.

 

Photo courtesy of Michael Rosnach

 

Welcome Dr. Cera and Dr. Lee! April 3rd, 2017

The DBG would like to extend a warm welcome to our new postdoctoral fellows, Luca Cera & Keel Yong Lee. Luca comes to us from Berlin, German, where he recently completed his Ph.D. in Chemistry under the guidance of Prof. Dr. Christoph A. Schalley. Keel Yong recently completed his Ph.D. in Prof. Kwanwoo Shin’s lab at Sogang University in Seoul, South Korea. We are looking forward to expanding on our past collaborations with him.

Congratulations to Karaghen Hudson, Leila Deravi & Nina Sinatra on the cover of Macromolecular Materials and Engineering! March 27th, 2017

Parker Lab Artist Karaghen Hudson’s illustration accompanying Leila Deravi & Nina Sinatra’s paper “Design and Fabrication of Fibrous Nanomaterials Using Pull Spinning” was chosen for the March 2017 cover of Macromolecular Materials and Engineering.

 

 

Pull spinning is a new nanofiber manufacturing technique that uses a high-speed rotating bristle to draw anisotropic nanofibers from a polymer solution. The versatile structure and composition of scaffolds formed using pull spinning enables a wide range of applications, including muscle tissue engineering and textile design.