The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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Post-Doc Opening: Rapid Manufacturing of Regenerative Heart Valves May 7th, 2018

Prof. Kevin Kit Parker’s Disease Biophysics Group at the Harvard University Wyss Institute for Biologically Inspired Engineering seeks a talented post-doctoral fellow to work on the rapid manufacturing of regenerative heart valves, or JetValves. The candidate will use the proprietary rotary jet spinning technologies developed in the Parker lab to design, build, and test heart valve replacements using natural and synthetic polymeric nanofibers. The goal of this translational project – which is part of an international collaboration with the University of Zurich in Switzerland – is to complete the preclinical characterization of JetValves in preparation for a first-in-man clinical trial.

 

Application Procedure

Interested candidates should submit their application packet to Prof. Kevin Kit Parker (kkparker@g.harvard.edu) and his admin assistant Dr. Ben Smith (bdsmith@g.harvard.edu) as a single pdf file with the following documents: cover letter, CV, 3 relevant papers, and the names of three referees.

More details found at: https://wyss.harvard.edu/job/rapid-manufacturing-of-regenerative-heart-valves/

 

Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

DBGer Professors!! May 4th, 2018

Kit had an opportunity to spend time with some of the former DBGers who have now joined the ranks of the community of scholars. At the Keystone Conference in Big Sky Montana, he spent time with (shown in photo) Professor Megan McCain from the University of Southern California, Professor Ashutosh Agarwal at the University of Miami, and the newly minted Professor Ben Maoz, Tel Aviv University! On his recent trip to Seoul, Kit spent time with Professor Hyunksuk Lee at Yonsei University. We are proud of all of our alumni and grateful to see them out doing great things!

Congrats DBGers Medical School Bound! May 4th, 2018

The DBG celebrates a 100% success rate with its medical school applicants this year. Tara Murty will be attending Stanford Medical School, Madeleine Dahl will be attending Robert Wood Johnson School of Medicine, Charles Alver will enter the Medical Scientist Training Program at the University of Miami, and Danielle Sawka has been accepted to the BA,MD program at Brown University. Congratulations!!

Congratulations to John Ferrier for winning the 2017 LG UltraWide Festival October 18th, 2017

The DBG would like to congratulate one of our lab managers, John Ferrier, on winning the 2017 LG UltraWide Festival which was hosted by Linus Tech Tips and Austin Evans!

DBG Nanofibers Merge with Art by Carla Ciuffo August 23rd, 2017

The Disease Biophysics Group would like to congratulate and thank Tennessee based artist Carla Ciuffo in her efforts to integrate our nanofibers into her art exhibit “Cosmic Garden” at Tinney Contemporary, opening this Saturday.

“Tundra,” 2017, polished acrylic with floating museum back frame, 48×48 on display at Tinney Contemporary. (Photo: Photo courtesy of the gallery)

Featured Publications

109. Lee KY, Park S-J, Lee KA, Kim S-H, Kim H, Meroz Y, Mahadevan L, Jung K-H, Ahn TK, Parker KK, Shin K. Photosynthetic Artificial Organelles Sustain and Control ATP-Dependent Reactions in a Protocellular System. Nat Biotechnol. 2018 May 28. doi: 10.1038/nbt.4140.

108. Ahn S, Ardoña HAM, Lind JU, Eweje F, Kim SL, Gonzalez GM, Liu Q, Zimmerman JF, Pyrgiotakis G, Zhang Z, Beltran-Huarac J, Carpinone P, Moudgil BM, Demokritou P, Parker KK. Mussel-Inspired 3D Fiber Scaffolds for Heart-on-a-Chip Toxicity Studies of Engineered Nanomaterials. Anal Bioanal Chem. 2018 May 10. doi: 10.1007/s00216-018-1106-7; PubMed PMID: 29744562.

107. Pasqualini FS, Agarwal A, O’Connor BB, Liu Q, Sheehy SP, Parker KK. Traction force microscopy of engineered cardiac tissues. PLOS One. 2018 Mar 28;13(3):e0194706. doi: 10.1371/journal.pone.0194706; PubMed PMID: 29590169; PubMed Central PMCID: PMC5874032.

106. Chantre CO, Campbell PH, Golecki HM, Buganza AT, Capulli AK, Deravi LF, Dauth S, Sheehy SP, Paten JA, Gledhill K, Doucet YS, Abaci HE, Ahn S, Pope BD, Ruberti JW, Hoerstrup SP, Christiano AM, Parker KK Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model Biomaterials. 2018 Jun. doi: 10.1016/j.biomaterials.2018.03.006

105. Seungkuk Ahn, Keel Yong Lee, Kwanwoo Shin, Parker KK Formation of Multi-Component Extracellular Matrix Protein Fibers Scientific Reports. 2018 Jan 30. doi: 10.1038/s41598-018-20371-8

104. Ahn S, Chantre CO, Gannon AR, Lind JU, Campbell PH, Grevesse T, O’Connor BB, Parker KK Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing Advanced Healthcare Materials. 2018 Jan 23. doi: 10.1002/adhm.201701175

103. Janna C Nawroth, Lisa L Scudder, Ryan T Halvorson, Jason Tresback, John P Ferrier Jr, Sean P Sheehy, Alex Cho, Suraj Kannan, Ilona Sunyovszki, Josue A Goss, Patrick H Campbell and Parker KK Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications Biofabrication. 2018 Jan 17. doi: 10.1088/1758-5090/aa96de