The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

DBG Lab is Operational! March 15th, 2021

After 17 years of outstanding science in Cambridge, the DBG has moved to the Engineering School’s new campus in Allston. As of March 2, the lab is fully operational and has resumed experiments. Thank you to all alumni and current personnel for constantly raising the bar. Stand by for the next chapter of DBG science!

Congratulations to Dr. Megan McCain! March 10th, 2021

Our congratulations go out to DBG alumna, Dr. Megan McCain, who has recently received tenure at University of Southern California!

Farewell to Dr. Suhwan Kim! January 13th, 2021

Congratulations to Dr. Suhwan Kim, who has accepted a position as an Assistant Professor in the Department of Chemical Engineering at Dong-A University in Basun, South Korea! Dr. Kim was an integral part of our brain team for over a year as a postdoctoral fellow. We wish him the best on this next step in his career!

Inaugural Issue — Biophysics Reviews! January 4th, 2021

Dr. Kevin Kit Parker launched Biophysics Reviews, a new peer-reviewed journal for the biophysics research community on December 14. Produced by scientific publisher AIP Publishing, the aims to expand “on the tradition of excellence set by Applied Physics Reviews (APR) by publishing high impact, cutting edge research and reviews that are valuable for both emerging and experienced researchers”.

1. KK Parker, L Longobardi, A Sulicz. “Welcome to Biophysics Reviews, a big tent for the biophysics community”. Biophysics Reviews. 14 Dec 2020; 1(1); 010401.

A Belated Farewell and Congratulations to Dr. Ardoña! October 14th, 2020

Congratulations to Dr. Herdeline Ardoña, who has accepted a position as an Assistant Professor in the University of California Irvine Department of Chemical and Biomolecular Engineering. She joined the Disease Biophysics Group as a postdoctoral fellow in 2017 and was an essential part of our research and mentoring team. Best of luck to you as you settle in and get your research group up and running!

Featured Publications

143. Glieberman AL, Pope BD, Melton DA, Parker KK.Building Biomimetic Potency Tests for Islet Transplantation. Diabetes. Feb 2021; 70(2); 347-363. doi: 10.2337/db20-0297. PMID: 33472944.

142. Parker KK, Longobardi L, Sulicz A. Welcome to Biophysics Reviews, a big tent for the biophysics community. Biophysics Reviews. 14 Dec 2020; 1(1); 010401. DOI: 10.1063/5.0036408. [Editorial]

141. Pope BD, Warren CR, Dahl MO, Pizza CV, Henze DE, Sinatra NR, Gonzalez GM, Chang H, Liu Q, Gleiberman AL, Ferrier JP, Cowan CA, Parker KK. Fattening chips: hypertrophy, feeding, and fasting of human white adipocytes in vitro. Lab on a Chip. 21 Sept 2020; PMID: 33034335

140. Yadid M, Lind JU, Ardoña HAM, Sheehy SP, Dickinson LE, Eweje F, Bastings MCB, Pope B, O’Connor BB, Straubhaar JR, Budnik B, Kleber AG, Parker KK. Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. Science Translational Medicine. 2020 Oct 14; 12(565); eaax8005. doi: 10.1126/scitranslmed.aax8005. PMID: 33055246. [Cover]

139. Ahn S, Chantre CO, Ardoña HAM, Gonzalez GM, Campbell PH, Parker KK.Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β. Biomaterials. 2020 Oct; 255:120149. doi: 10.1016/j.biomaterials.2020.120149. Epub 2020 May 28. PMID: 32521331. Supplemental materials.

138. Aytac Z, Huang R, Vaze N, Xu T, Eitzer BD, Krol W, MacQueen LA, Chang H, Bousfield DW, Chan-Park MB, Ng KW, Parker KK, White JC, and Demokritou, P. Development of biodegradable and antimicrobial electrospun zein fibers for food packaging. ACS Sustainable Chem. Eng. 2020 Sep 21; 8(40):15354-15365.

137. Fioretta ES, Motta SE, Lintas Valentina, Loerakker S, Parker KK, Baaijens FPT, Falk V, Hoerstrup SP, and Emmert MY. Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity. Nat Rev Cardiol. 2020 Sep 9. doi: 10.1038/s41569-020-0422-8. Epub ahead of print. PMID: 32908285.