The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

Congratulations to John Ferrier for winning the 2017 LG UltraWide Festival October 18th, 2017

The DBG would like to congratulate one of our lab managers, John Ferrier, on winning the 2017 LG UltraWide Festival which was hosted by Linus Tech Tips and Austin Evans!

DBG Nanofibers Merge with Art by Carla Ciuffo August 23rd, 2017

The Disease Biophysics Group would like to congratulate and thank Tennessee based artist Carla Ciuffo in her efforts to integrate our nanofibers into her art exhibit “Cosmic Garden” at Tinney Contemporary, opening this Saturday.

“Tundra,” 2017, polished acrylic with floating museum back frame, 48×48 on display at Tinney Contemporary. (Photo: Photo courtesy of the gallery)

Thank you to our Summer Students! August 16th, 2017

Thank you to all the undergraduate students who spent time working in the lab over the summer. We wish you all the best this school year!

 

Jenny Wang, United States Military Academy at West Point
Daniel Gray, United States Military Academy at West Point
Nikita Pereverzin, United States Military Academy at West Point
Kathryn Dula, United States Military Academy at West Point
Daniel Drennan, Nicholls State University
Michael Ferris, James Madison University
Karla Rivera, Barry University
John Doyle, University of Massachusetts at Lowell
Madeleine Dahl, Salem State University
Nikita Budnik, McGill University
Karaghen Hudson, Harvard University
Sayo Eweje, Harvard University
Michael Peters, Harvard University
Gabriela Berner, Harvard University

Welcome Dr. Ardoña! August 15th, 2017

The DBG would like to extend a warm welcome to our newest postdoctoral fellow, Dr. Herdeline Ardoña. Herdeline recently completed her Ph.D. in Chemistry at Johns Hopkins University,  where she was a part of Prof. Tovar’s lab.  Welcome, Herdeline!

Welcome Dr. Liu! June 23rd, 2017

The DBG would like to extend a warm welcome to our newest postdoctoral fellow, Dr. Qihan Liu. Qihan completed his Ph.D. in Prof. Zhigang Suo’s lab here at Harvard University, where he focused on the mechanics and physics of soft materials.  Welcome, Qihan!

Featured Publications

107. Pasqualini FS, Agarwal A, O’Connor BB, Liu Q, Sheehy SP, Parker KK. Traction force microscopy of engineered cardiac tissues. PLOS One. 2018 Mar 28;13(3):e0194706. doi: 10.1371/journal.pone.0194706; PubMed PMID: 29590169; PubMed Central PMCID: PMC5874032.

106. Chantre CO, Campbell PH, Golecki HM, Buganza AT, Capulli AK, Deravi LF, Dauth S, Sheehy SP, Paten JA, Gledhill K, Doucet YS, Abaci HE, Ahn S, Pope BD, Ruberti JW, Hoerstrup SP, Christiano AM, Parker KK Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model Biomaterials. 2018 Jun. doi: 10.1016/j.biomaterials.2018.03.006

105. Seungkuk Ahn, Keel Yong Lee, Kwanwoo Shin, Parker KK Formation of Multi-Component Extracellular Matrix Protein Fibers Scientific Reports. 2018 Jan 30. doi: 10.1038/s41598-018-20371-8

104. Ahn S, Chantre CO, Gannon AR, Lind JU, Campbell PH, Grevesse T, O’Connor BB, Parker KK Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing Advanced Healthcare Materials. 2018 Jan 23. doi: 10.1002/adhm.201701175

103. Janna C Nawroth, Lisa L Scudder, Ryan T Halvorson, Jason Tresback, John P Ferrier Jr, Sean P Sheehy, Alex Cho, Suraj Kannan, Ilona Sunyovszki, Josue A Goss, Patrick H Campbell and Parker KK Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications Biofabrication. 2018 Jan 17. doi: 10.1088/1758-5090/aa96de

102. Johan U. Lind, Moran Yadid, Ian Perkins, Blakely B. O’Connor, Feyisayo Eweje, Christophe O. Chantre, Matthew A. Hemphill, Hongyan Yuan, Patrick H. Campbell, Joost J. Vlassak and Parker KK Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening. Lab Chip. 2017 Oct 4. doi: 10.1039/c7lc00740j. [Epub ahead of print]

101. Yuan H, Marzban B, Parker KK Myofibrils in Cardiomyocytes Tend to Assemble Along the Maximal Principle Stress Directions. J Biomech Eng. 2017 Aug 31. doi: 10.1115/1.4037795. [Epub ahead of print]