Images from the DBG

Using micro-contact printing techniques, extracellular matrix proteins can be deposited on substrates in custom shapes with micron scale resolution; by controlling ECM shape, pattern, size, etc we can recapitulate native tissue structure and alignment in our in vitro assays. Here is an aligned diamond tissue composed of porcine valve interstitial cells [blue: nucleus, red: vimentin, white: f-actin, green: alpha-SMA].  Photo by Andrew Capulli, Parker Research Group.