Design standards for engineered tissues
Publication information:
56 ., Nawroth JC, and Parker KK. 2013. “Design Standards for Engineered Tissues”. Biotechnology Advances, 31, 5, Pp. 632-7
Abstract
Traditional technologies are required to meet specific, quantitative standards of safety and performance. In tissue engineering, similar standards will have to be developed to enable routine clinical use and customized tissue fabrication. In this essay, we discuss a framework of concepts leading towards general design standards for tissue-engineering, focusing in particular on systematic design strategies, control of cell behavior, physiological scaling, fabrication modes and functional evaluation.