The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
Read More »

What's New

Congratulations to Ian Perkins & Alex Cho! January 5th, 2017

The DBG would like to congratulate Ian Perkins and Alex Cho who both graduated from Northeastern University in December. Ian received his B.S. in Mechanical Engineering and Alex his B.S. in Biology. We would like to thank you both for your significant contributions to the DBG over the past several years, and we are grateful that you are both continuing with us in the lab this semester!

Congratulations Dr. Capulli! December 15th, 2016

Congratulations to Dr. Andrew Capulli who successfully defended his dissertation in December, and will continue in the DBG as a Postdoctoral Fellow.

Congratulations Dr. Nesmith! December 15th, 2016

Congratulations to Dr. Peyton Nesmith who successfully defended his dissertation last month.  We wish him the best of luck as he returns to the University of Alabama to complete his M.D.

Congratulations to Parker Lab Post-doc Johan Lind, Ph.D., on the publication of his Heart-on-a-Chip paper in Nature Materials on October 24! October 25th, 2016

Robotic Stingray wins Popular Science “Best of What’s New” Award October 19th, 2016

Congratulations to Professor Kit Parker and Sung-Jin Park on the Robotic Stingray being named a winner in the Engineering Category of Popular Science’s “Best of What’s New” 2016.  Read more here.
ray

 

 

 

 

 

 

 

 

Photo courtesy of Karaghen Hudson and Michael Rosnach

Featured Publications

93.  Deravi LF, Sinatra NR, Chantre CO, Nesmith AP, Yuan H, Deravi SK, Goss JA, MacQueen LA, Badrossamy MR, Gonzalez GM, Phillips MD, Parker KKDesign and fabrication of fibrous nanomaterials using pull spinning. Macromolecular Materials and Engineering. 17 January 2017. DOI: 10.1002/mame.201600404. [Epub ahead of print].

92.  Dauth S, Maoz BM, Sheehy SP, Hemphill MA, Murty T, Macedonia MK, Greer AM, Budnik B, Parker KK. Neurons derived from different brain regions are inherently different in vitro: A novel multiregional brain-on-a-chip. Journal of Neurophysiology.  28 December 2016. doi: 10.1152/jn.00575.2016. [Epub ahead of print].

 

91.  Benam KH, Novak R, Nawroth J, Hirano-Kobayashi M, Ferrante TC, Choe Y, Prantil-Baun R, Weaver JC, Bahinski A, Parker KK, Ingber DE. Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip. Cell Systems. 27 October 2016. doi:10.1016/j.cels.2016.10.003 [Epub ahead of print].

90. Lind JU, Busbee TA, Valentine AD, Pasqualini FS, Yuan H, Yadid M, Park SJ, Kotikian A, Nesmith AP, Campbell PH, Vlassak JJ, Lewis JA, Parker KK. Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing. Nature Materials. 24 October 2016; doi: 10.1038/nmat4782.

89. Gonzalez GM, MacQueen LA, Lind JU, Fitzgibbons SA, Chantre CO, Huggler I, Golecki HM, Goss JA, Parker KK. Production of synthetic, para-aramid and biopolymer nanofibers by immersion rotary jet-spinning. Macromolecular Materials and Engineering. 7 October 2016; doi: 10.1002/mame.201600365 [Epub ahead of print].

88. Pasqualini FS, Emmert MY, Parker KK, Hoerstrup SP.  Organ Chips: Quality Assurance Systems in Regenerative Medicine.  Clin Pharmacol Ther. 2016 Oct 6. doi: 10.1002/cpt.527. [Epub ahead of print]

87. Nesmith, AP, Wagner MA, Pasqualini FS, O’Connor BB, Pincus MJ, August PR, Parker KK. A human in vitro model of Duchenne muscular dystrophy muscle formation and contractility.  The Journal of Cell Biology. 3 October 2016; doi: 10.1083/jcb.201603111.