The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

2018 DBG Family Day November 30th, 2018

Left our microscopes at the lab and did Play-Doh science at the Miller Alehouse in Watertown. Critics were small, but fair. Dr. Huibin Chang impresses judges during Play-Doh model competition with an outstanding score of 73.5 out of 20!

Our thanks to our lab members and their families, whose hard work and support makes everything possible.



Welcome, Dr. Suji Choi and Dr. Sarah Motta! October 5th, 2018

The DBG would like to extend a warm welcome to our new postdoctoral fellows, Suji Choi and Sarah Motta. Suji joins us from Seoul National University, where she completed her Ph.D. in Chemical and Biological Engineering in Prof. Dae-hyeong Kim’s Flextronics group. Sarah recently completed her Ph.D. at the Institute for Regenerative Medicine in Zurich in Tissue Engineering and Regenerative Medicine. We are excited for both of them to join us!

Welcome, Huibin! September 5th, 2018

The DBG welcomes Post-Doctoral Fellow Huibin Chang, who joined the group September 1. Huibin joins us from Georgia Tech, where he recently completed his Ph.D. in Materials Science and Engineering. Welcome, Huibin!

Congressional Staffers Visit the DBG August 31st, 2018

The DBG welcomed several opportunities so far in 2018 to discuss Federal budget appropriations to the National Institutes of Health and the Department of Defense. After discussions with staffers from Senator Elizabeth Warren (D-MA), Congresswoman Katherine Clark (D-MA), and the Senate Armed Services Committee regarding our experiences with the various offices of the DoD and NIH, we showed our work and introduced the professional staff and trainees within the laboratory. Over the years we have enjoyed interactions with a variety of elected officials and Congressional staffers who have requested to hear about our work and the challenges with funding research at the cutting edge.

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Farewell John August 20th, 2018

Congratulations to John P. Ferrier Jr., who was accepted into the Northeastern University Physics Ph.D. program in Boston. He moves to Northeastern in September 2018. Congratulations, John!

Featured Publications

113. Liu Q, Parker KK. A viscoelastic beam theory of polymer jets with application to rotary jet spinning. J. EML. 2018 Nov. doi: 10.1016/j.eml.2018.10.005

112. Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, Budnik B, Ingber DE, Parker KK. A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. Nat. Biotechnol. 2018 Aug 20. doi: 10.1038/nbt.4226

111. MacQueen LA, Sheehy SP, Chantre CO, Zimmerman JF, Pasqualini FS, Liu X, Goss JA, Campbell PH, Gonzalez GM, Park SJ, Capulli AK, Ferrier JP, Kosar TF, Mahadevan L, Pu WT, Parker KK. A tissue-engineered scale model of the heart ventricle. Nat. Biomed. Eng. 2018 July 23. doi: 10.1038/s41551-018-0271-5.

110. Sinatra NR, Ranzani T, Vlassak JJ, Parker KK, Wood RJ. Nanofiber-reinforced soft fluidic micro-actuators. J. Micromech. Microeng. 2018 May 21. doi: 10.1088/1361-6439/aab373.

109. Lee KY, Park S-J, Lee KA, Kim S-H, Kim H, Meroz Y, Mahadevan L, Jung K-H, Ahn TK, Parker KK, Shin K. Photosynthetic Artificial Organelles Sustain and Control ATP-Dependent Reactions in a Protocellular System. Nat Biotechnol. 2018 May 28. doi: 10.1038/nbt.4140.

108. Ahn S, Ardoña HAM, Lind JU, Eweje F, Kim SL, Gonzalez GM, Liu Q, Zimmerman JF, Pyrgiotakis G, Zhang Z, Beltran-Huarac J, Carpinone P, Moudgil BM, Demokritou P, Parker KK. Mussel-Inspired 3D Fiber Scaffolds for Heart-on-a-Chip Toxicity Studies of Engineered Nanomaterials. Anal Bioanal Chem. 2018 May 10. doi: 10.1007/s00216-018-1106-7; PubMed PMID: 29744562.

107. Pasqualini FS, Agarwal A, O’Connor BB, Liu Q, Sheehy SP, Parker KK. Traction force microscopy of engineered cardiac tissues. PLOS One. 2018 Mar 28;13(3):e0194706. doi: 10.1371/journal.pone.0194706; PubMed PMID: 29590169; PubMed Central PMCID: PMC5874032.