The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

Congratulations to John Ferrier for winning the 2017 LG UltraWide Festival October 18th, 2017

The DBG would like to congratulate one of our lab managers, John Ferrier, on winning the 2017 LG UltraWide Festival which was hosted by Linus Tech Tips and Austin Evans!

DBG Nanofibers Merge with Art by Carla Ciuffo August 23rd, 2017

The Disease Biophysics Group would like to congratulate and thank Tennessee based artist Carla Ciuffo in her efforts to integrate our nanofibers into her art exhibit “Cosmic Garden” at Tinney Contemporary, opening this Saturday.

“Tundra,” 2017, polished acrylic with floating museum back frame, 48×48 on display at Tinney Contemporary. (Photo: Photo courtesy of the gallery)

Thank you to our Summer Students! August 16th, 2017

Thank you to all the undergraduate students who spent time working in the lab over the summer. We wish you all the best this school year!

 

Jenny Wang, United States Military Academy at West Point
Daniel Gray, United States Military Academy at West Point
Nikita Pereverzin, United States Military Academy at West Point
Kathryn Dula, United States Military Academy at West Point
Daniel Drennan, Nicholls State University
Michael Ferris, James Madison University
Karla Rivera, Barry University
John Doyle, University of Massachusetts at Lowell
Madeleine Dahl, Salem State University
Nikita Budnik, McGill University
Karaghen Hudson, Harvard University
Sayo Eweje, Harvard University
Michael Peters, Harvard University
Gabriela Berner, Harvard University

Welcome Dr. Ardoña! August 15th, 2017

The DBG would like to extend a warm welcome to our newest postdoctoral fellow, Dr. Herdeline Ardoña. Herdeline recently completed her Ph.D. in Chemistry at Johns Hopkins University,  where she was a part of Prof. Tovar’s lab.  Welcome, Herdeline!

Welcome Dr. Liu! June 23rd, 2017

The DBG would like to extend a warm welcome to our newest postdoctoral fellow, Dr. Qihan Liu. Qihan completed his Ph.D. in Prof. Zhigang Suo’s lab here at Harvard University, where he focused on the mechanics and physics of soft materials.  Welcome, Qihan!

Featured Publications

102. Johan U. Lind, Moran Yadid, Ian Perkins, Blakely B. O’Connor, Feyisayo Eweje, Christophe O. Chantre, Matthew A. Hemphill, Hongyan Yuan, Patrick H. Campbell, Joost J. Vlassak and Parker KK Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening. Lab Chip. 2017 Oct 4. doi: 10.1039/c7lc00740j. [Epub ahead of print]

101. Yuan H, Marzban B, Parker KK Myofibrils in Cardiomyocytes Tend to Assemble Along the Maximal Principle Stress Directions. J Biomech Eng. 2017 Aug 31. doi: 10.1115/1.4037795. [Epub ahead of print]

100. Generali M, Kehl D, Capulli AK, Parker KK, Hoerstrup SP, Weber B. Comparative analysis of poly-glycolic acid-based hybrid polymer starter matrices for in vitro tissue engineering. Colloids Surf B Biointerfaces. 2017 Jul 1;158:203-212. doi: 10.1016/j.colsurfb.2017.06.046. [Epub ahead of print]

99. Ko H, Deravi LF, Park SJ, Jang J, Lee T, Kang C, Lee JS, Parker KK, Shin K. Fabrication of Millimeter-Long Carbon Tubular Nanostructures Using the Self-Rolling Process Inherent in Elastic Protein Layers. Adv Mater. 2017 Jun 19. doi: 10.1002/adma.201701732. [Epub ahead of print]

98. Maoz BM, Herland A, Henry OYF, Leineweber WD, Yadid M, Doyle J, Mannix R, Kujala VJ, Fitzgerald EA, Parker KK, Ingber DE. Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities. Lab Chip. 2017 June 7. doi: 10.1039/c7lc00412e[Epub ahead of print]

97. Capulli AK, Emmert MY, Pasqualini FS, Kehl D, Caliskan E, Lind JU, Sheehy SP, Park SJ, Ahn S, Weber B, Goss JA, Hoerstrup SP, Parker KK. JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement.
Biomaterials. 2017 Apr 18;133:229-241. doi: 10.1016/j.biomaterials.2017.04.033. [Epub ahead of print]
PMID: 28445803

96. Emmert MY, Wolint P, Jakab A, Sheehy SP, Pasqualini FS, Nguyen TD, Hilbe M, Seifert B, Weber B, Brokopp CE, Macejovska D, Caliskan E, von Eckardstein A, Schwartlander R, Vogel V, Falk V, Parker KK, Gyöngyösi M, Hoerstrup SP. Safety and efficacy of cardiopoietic stem cells in the treatment of post-infarction left-ventricular dysfunction – From cardioprotection to functional repair in a translational pig infarction model.
Biomaterials. 2017 Apr;122:48-62. doi: 10.1016/j.biomaterials.2016.11.029. Epub 2016 Nov 23.
PMID: 28107664