The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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Congratulations to Sung Jin Park, whose paper "Phototactic Guidance of a tissue-engineered soft-robotic ray" is featured on the cover of the July 8 issue of Science!


What's New

Thank you summer students! August 30th, 2016

Thank you to all the undergraduate students who spent time working in the lab over the summer. We wish you all the best this school year!

Alex Cho, Northeastern University
Alexandra Bell, United States Military Academy at West Point
Aviv Preminger, Weslyan University
Beom Jin An, United States Military Academy at West Point
Brian Fountaine, Northeastern University
Charlie Alver, Harvard University
Daniel Villarreal, Bunker Hill Community College
Ian Perkins, Northeastern University
John Doyle, Bunker Hill Community College
Joseph Schlessinger, United States Military Academy at West Point
Karaghen Hudson, Harvard University
Kenneth Sims, United States Military Academy at West Point
Lauren Dickinson, Hendrix College
Madeleine Dahl, Bunker Hill Community College
Natalie Nepa, United States Military Academy at West Point
Nikita Budnik, McGill University
Oscar Deal, United States Military Academy at West Point
Ryan Halvorson, Harvard University
Sayo Eweje, Harvard University
Zachary Riggenbach, United States Military Academy at West Point

 

Welcome, John! August 10th, 2016

The DBG would like to welcome Post-Doctoral Fellow John Zimmerman, who joined the group August 3.  John comes to us from the  University of Chicago, where he recently completed his Ph.D. in Chemistry.  We are excited to have John here!

Welcome, General Phillips! August 1st, 2016

Brigadier General Michael D. Phillips, Ph.D. (USA, Retired) has joined the Disease Biophysics Group, effective August 1, continuing a longstanding collaboration. Most recently, General Phillips served as a Professor of Applied Mathematics and Head of the Department of Mathematical Sciences at the United States Military Academy at West Point. We are looking forward to having him with us full time!

Welcome back, Professor Shin! July 18th, 2016

The DBG would like to welcome Professor Kwanwoo Shin who is visiting us from Sogang University in Seoul, Korea. Professor Shin is the Chair of the Department of Chemistry and the Director of the Institute of Biological Interfaces. We are grateful for our continued collaboration and partnership with Professor Shin and his lab!

Welcome, Summer Students! July 18th, 2016

The DBG would like to extend a warm welcome to the new undergraduate students working in the lab this summer:

Beom Jin An – West Point

Natalie Nepa – West Point

Kenneth Sims – West Point

Alexandra Bell – West Point

Zachary Riggenback – West Point

Oscar Deal – West Point

Joseph Schlessinger – West Point

Madeline Dahl – Bunker Hill Community College

Daniel Villarreal – Bunker Hill Community College

Brian Fountaine – Northeastern University

Aviv Preminger – Weslyan University

Nikita Budnik – McGill University

Lauren Dickinson – Hendrix College

Featured Publications

84. Park SJ, Gazzola M, Park KS, Park S, DiSanto V, Blevins EL, Lind JU, Campbell PH, Dauth S, Capulli AK, Pasqualini FS, Ahn S, Cho A, Yuan H, Maoz BM, Vijaykumar R, Choi JW, Deisseroth K, Lauder GV, Mahadevan L, Parker KK. Phototactic guidance of a tissue-engineered soft-robotic ray. Science. 2016 July 8; doi: 10.1126/science.aaf4292

83.  Pope BD, Warren CR, Parker KK, Cowan, CA. Microenvironmental control of adipocyte fate and function. Trends in Cell Biology. 2016 June 5; doi: http://dx.doi.org/10.1016/j.tcb.2016.05.005 [Epub ahead of print]

82.  Capulli AK, MacQueen LA, O’Connor BB, Dauth S, Parker KK. Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduced contractility in vitro. Cardiovascular Pathology. 2016 Apr 25; 25(4):316-324. doi: 10.1016/j.carpath.2016.04.004.  [Epub ahead of print]

81.  Capulli AK, MacQueen LA, Sheehy SP, Parker KK.  Fibrous scaffolds for building hearts and heart parts.  Adv. drug delivery reviews. 2016 Jan 15. 96, 83-102. doi:10.1016/j.addr.2015.11.020

80. Aratyn-Schaus Y, Pasqualini FS, Yuan H, McCain ML, Ye GJ, Sheehy SP, Campbell PH, Parker KKCoupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. J Cell Biol. 2016 Feb 8. doi: 10.1083/jcb.201508026

79. Dauth S, Grevesse T, Pantazopoulos H, Campbell PH, Maoz, BM, Berretta S and Parker KK. Extracellular matrix protein expression is brain region dependent. J Comp Neurol. 2016 Jan 18. doi: 10.1002/cne.23965. [Epub ahead of print]

78.  Horton RE, Yadid M, McCain, ML, Sheehy SP, Pasqualini FS, Park SJ, Cho A, Campbell P, Parker KK. Angiotensin II Induced Cardiac Dysfunction on a Chip. PLos ONE. 2016; 1(1): e0146415. doi:10.1371/journal.pone.0146415