The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

2019 DBG Retreat January 17th, 2019

The Disease Biophysics Group just returned from its annual retreat! For two days, DBGers presented research updates to the group and our visiting collaborators.

2018 HIRN Meeting at Harvard January 12th, 2019

In December 2018 we hosted the Human Islet Research Network’s (HIRN) NIH investigator meeting. Professor Parker treated the visitors to BBQ brisket and chicken as they discussed the state of the field and toured through DBG labs for numerous demonstrations.

2018 DBG Family Day November 30th, 2018

Left our microscopes at the lab and did Play-Doh science at the Miller Alehouse in Watertown. Critics were small, but fair. Dr. Huibin Chang impresses judges during Play-Doh model competition with an outstanding score of 73.5 out of 20!

Our thanks to our lab members and their families, whose hard work and support makes everything possible.

Welcome, Dr. Suji Choi and Dr. Sarah Motta! October 5th, 2018

The DBG would like to extend a warm welcome to our new postdoctoral fellows, Suji Choi and Sarah Motta. Suji joins us from Seoul National University, where she completed her Ph.D. in Chemical and Biological Engineering in Prof. Dae-hyeong Kim’s Flextronics group. Sarah recently completed her Ph.D. at the Institute for Regenerative Medicine in Zurich in Tissue Engineering and Regenerative Medicine. We are excited for both of them to join us!

Welcome, Huibin! September 5th, 2018

The DBG welcomes Post-Doctoral Fellow Huibin Chang, who joined the group September 1. Huibin joins us from Georgia Tech, where he recently completed his Ph.D. in Materials Science and Engineering. Welcome, Huibin!

Featured Publications

116. Parker KK. Designer Assays for Your Sick, Subdivided Heart. Cell. 2019 Jan 28. doi: 10.1016/j.cell.2019.01.028

115. Zimmerman JF, Ardoña HAM, Pyrgiotakis G, Dong J, Moudgil B, Demokritou P, Parker KK. Scatter Enhanced Phase Contrast Microscopy for Discriminating Mechanisms of Active Nanoparticle Transport in Living Cells. Nanoletters. 2019 Jan 7; doi: 10.1021/acs.nanolett.8b03903

114. Liu Q, Parker KK. A viscoelastic beam theory of polymer jets with application to rotary jet spinning. Extreme Mechanics Letters. 2018 Nov. doi: 10.1016/j.eml.2018.10.005

113. Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, Budnik B, Ingber DE, Parker KK. A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. Nat. Biotechnol. 2018 Aug 20. doi: 10.1038/nbt.4226

112. MacQueen LA, Sheehy SP, Chantre CO, Zimmerman JF, Pasqualini FS, Liu X, Goss JA, Campbell PH, Gonzalez GM, Park SJ, Capulli AK, Ferrier JP, Kosar TF, Mahadevan L, Pu WT, Parker KK. A tissue-engineered scale model of the heart ventricle. Nat. Biomed. Eng. 2018 July 23. doi: 10.1038/s41551-018-0271-5.

111. Sinatra NR, Ranzani T, Vlassak JJ, Parker KK, Wood RJ. Nanofiber-reinforced soft fluidic micro-actuators. J. Micromech. Microeng. 2018 May 21. doi: 10.1088/1361-6439/aab373.

110. Lee KY, Park S-J, Lee KA, Kim S-H, Kim H, Meroz Y, Mahadevan L, Jung K-H, Ahn TK, Parker KK, Shin K. Photosynthetic Artificial Organelles Sustain and Control ATP-Dependent Reactions in a Protocellular System. Nat Biotechnol. 2018 May 28. doi: 10.1038/nbt.4140.