The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

The latest on our Art & Science Collaboration November 16th, 2015

Check out this article from for the latest news on our collaboration with artist Carla Ciuffo:

Welcome to the DBG! October 21st, 2015

The DBG would like to welcome our new Post-Doctoral Fellow Adrian Buganza Tepole. Adrian comes to us from Stanford University, where he recently completed his Ph.D. in Mechanical Engineering. We are excited to have Adrian join us!

Merging Art and Science September 17th, 2015

Recently the DBG had the pleasure of hosting Nashville, TN based artist Carla Ciuffo for a collaboration with our Nanofibers team, resulting in a new traveling museum exhibit titled “Nano . Stasis” The objective of this multimedia exhibition is to unify a stunning advance in science with its artistic counterpart, in effect emphasizing how creativity, beauty and science are truly intertwined. Learn more about how she is merging art with science here:

Thank you and Farewell Summer Students! September 10th, 2015

Thank you to all the undergraduate students who spent time working in the lab over the summer. We wish you all the best this school year!

Joe Festa, Harvard University
Ryan Halvorson, Harvard University
Charlie Alver, Harvard University
Yinka Ogunbiyi, Harvard University
John Doyle, Bunker Hill Community College
Jorge Jiminez, University of Rochester
Mary Kate Macedonia, Case Western Reserve University
Taler Brazelle, United States Military Academy at West Point
Jack Ward, United States Military Academy at West Point
Kevin Talty, United States Military Academy at West Point
Ginny Phillips, United States Military Academy at West Point
Thomas Manuel, Mississippi State University
Adrian Ledesma-Mendoza, University of New Mexico
William Mehalick, Bunker Hill Community College
Joy Rosa-Jackson, Howard University

Welcome John Ferrier! September 10th, 2015

The DBG would like to welcome John Ferrier, our newest lab manager, who joined the group on June 1st. John is a 2015 graduate of The University of Central Arkansas where he studied Physics & Math.

Featured Publications

77. Maia PD, Hemphill MA, Zehnder B, Zhang C, Parker KK, Kutz JN.  Diagnostic tools for evaluating the impact of Focal Axonal Swellings arising in neurodegenerative diseases and/or traumatic brain injury. J Neurosci Methods. 2015 Sept 30;253:233-243. Epub 2015 Jul 16.

76. Ahn S, Deravi LF, Park SJ, Dabiri BE, Kim JS, Parker KK, Shin K. Self-organizing large-scale extracellular-matrix protein networks. Adv Mater. 2015 May 13;27(18):2838-45. Epub 2015 Mar 31.

75. Lee H, Adams WJ, Alford PW, McCain ML, Feinberg AW, Sheehy SP, Goss JA, Parker KK. Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes. Exp Biol Med (Maywood). 2015 Nov; 240(11):1543-54. Epub 2015 Apr 23.

74. Drew NK, Eagleson MA, Baldo DB Jr, Parker KK, Grosberg A. Metrics for assessing cytoskeletal orientational correlations and consistency. PLoS Comput Biol. 2015 Apr 7;11(4).

73. Grevesse T, Dabiri BE, Parker KK, Gabriele S. Opposite rheological properties of neuronal microcompartments predict axonal vulnerability in brain injury. Sci Rep. 2015 Mar 30;5:9475.

72. Hemphill MA, Dauth S, Yu CJ, Dabiri BE, Parker KK. Traumatic Brain Injury and the Neuronal Microenvironment: A Potential Role for Neuropathological Mechanotransduction. Neuron. 2015 Mar 18;85(6):1177-1192.

71. Pasqualini FS, Sheehy SP, Agarwal A, Aratyn-Schaus Y, Parker KK. Structural Phenotyping of Stem Cell Derived Cardiomyocytes. Stem Cell Reports. 2015 Mar 10;4(3):340-7.