The Disease Biophysics Group (DBG) at Harvard University is an interdisciplinary team of biologists, physicists, engineers and material scientists actively researching the structure/function relationship in cardiac, neural, and vascular smooth muscle tissue engineering.
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What's New

Welcome 2019 Summer Students! June 17th, 2019

The Disease Biophysics Group welcomes our 2019 summer students! From left to right: Rudy Gabardi, Carlos Marquez, James Ikeda, Christina Pizza, Danielle Gamboa, and Riley Flores. Best of luck on your summer research projects!

Congratulations to our new Ph.D.’s! June 7th, 2019

Congratulations to our newest PhD recipients Grant Gonzalez and Seungkuk Ahn! We thank them for their excellent achievements, and are looking forward to seeing their future work.

The Stingray goes to Paris! March 26th, 2019

The Disease Biophysics Group is at the Pompidou Centre! The centre’s Designing the Living exhibit is part of the Mutations/Créations 3 program. It includes our soft-robotic ray, featured on the cover of Science (Vol 353, Issue 6295; 08 July 2016). The exhibit showcases the interplay of bioengineering with art, and was curated by Marie-Ange Brayer and Olivier Zeitoun. A video of the exhibit can be found on the Pompidou Centre program page.

2019 DBG Retreat January 17th, 2019

The Disease Biophysics Group just returned from its annual retreat! For two days, DBGers presented research updates to the group and our visiting collaborators.

2018 HIRN Meeting at Harvard January 12th, 2019

In December 2018 we hosted the Human Islet Research Network’s (HIRN) NIH investigator meeting. Professor Parker treated the visitors to BBQ brisket and chicken as they discussed the state of the field and toured through DBG labs for numerous demonstrations.

Featured Publications

117. Chantre CO, Hoerstrup SP, Parker KK. Engineering biomimetic and instructive materials for wound healing and regeneration. Biomedical Engineering. 2019 May 9; doi: 10.1016/j.cobme.2019.04.004

116. Parker KK. Designer Assays for Your Sick, Subdivided Heart. Cell. 2019 Jan 28. doi: 10.1016/j.cell.2019.01.028

115. Zimmerman JF, Ardoña HAM, Pyrgiotakis G, Dong J, Moudgil B, Demokritou P, Parker KK. Scatter Enhanced Phase Contrast Microscopy for Discriminating Mechanisms of Active Nanoparticle Transport in Living Cells. Nanoletters. 2019 Jan 7; doi: 10.1021/acs.nanolett.8b03903

114. Liu Q, Parker KK. A viscoelastic beam theory of polymer jets with application to rotary jet spinning. Extreme Mechanics Letters. 2018 Nov. doi: 10.1016/j.eml.2018.10.005

113. Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, Budnik B, Ingber DE, Parker KK. A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. Nat. Biotechnol. 2018 Aug 20. doi: 10.1038/nbt.4226

112. MacQueen LA, Sheehy SP, Chantre CO, Zimmerman JF, Pasqualini FS, Liu X, Goss JA, Campbell PH, Gonzalez GM, Park SJ, Capulli AK, Ferrier JP, Kosar TF, Mahadevan L, Pu WT, Parker KK. A tissue-engineered scale model of the heart ventricle. Nat. Biomed. Eng. 2018 July 23. doi: 10.1038/s41551-018-0271-5.

111. Sinatra NR, Ranzani T, Vlassak JJ, Parker KK, Wood RJ. Nanofiber-reinforced soft fluidic micro-actuators. J. Micromech. Microeng. 2018 May 21. doi: 10.1088/1361-6439/aab373.